BDBM50262453 CHEMBL479049::R/S-(2S,3S)-N-((3-methoxy-8-(trifluoromethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)-2-phenylpiperidin-3-amine

SMILES COc1cc2CCCC(c2cc1CN[C@H]1CCCN[C@H]1c1ccccc1)C(F)(F)F

InChI Key InChIKey=UOYMONBFUXQTMB-ZXNYFWILSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262453   

TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262453(CHEMBL479049 | R/S-(2S,3S)-N-((3-methoxy-8-(triflu...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed