BDBM50263476 CHEMBL477590::N-(2-chloro-6-methylphenyl)-1-(6-(4-(diethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-amine

SMILES CCN(CC)CCCCNc1cc(ncn1)-n1c(Nc2c(C)cccc2Cl)nc2ccccc12

InChI Key InChIKey=INMCMWSTQIGBFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263476   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263476(CHEMBL477590 | N-(2-chloro-6-methylphenyl)-1-(6-(4...)
Affinity DataIC50:  5.04E+3nMAssay Description:Inhibition of TEL fused Lck (unknown origin)-mediated proliferation of TEL-Lck transformed mouse BA/F3 cells after 48 hrs by bright-glo luciferase as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263476(CHEMBL477590 | N-(2-chloro-6-methylphenyl)-1-(6-(4...)
Affinity DataIC50:  789nMAssay Description:Inhibition of Lck by lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed