BDBM50263726 4-Fluoro-N-{[(5-methyl-6-oxo-6,11-dihydro-5H-dibenzo[b,e]azepin-11-ylmethyl)-carbamoyl]-methyl}-benzamide::CHEMBL490609

SMILES CN1c2ccccc2C(CNC(=O)CNC(=O)c2ccc(F)cc2)c2ccccc2C1=O

InChI Key InChIKey=HKIDSMNVQATMCD-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50263726   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263726(4-Fluoro-N-{[(5-methyl-6-oxo-6,11-dihydro-5H-diben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 transfected in Flp-inTM-CHOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263726(4-Fluoro-N-{[(5-methyl-6-oxo-6,11-dihydro-5H-diben...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263726(4-Fluoro-N-{[(5-methyl-6-oxo-6,11-dihydro-5H-diben...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50263726(4-Fluoro-N-{[(5-methyl-6-oxo-6,11-dihydro-5H-diben...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed