BDBM50264431 5-((5S)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile::CHEMBL491030

SMILES CC[C@@]1(OCC(=O)Nc2ccc(cc12)-c1ccc([nH]1)C#N)c1cccs1

InChI Key InChIKey=MVBYGXGTVIRVQD-FQEVSTJZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264431   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264431(5-((5S)-5-ethyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-te...)
Affinity DataIC50:  17.1nMAssay Description:Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed