BDBM50264574 CHEMBL4090064
SMILES Cc1cc(C)cc(c1)C1CCCN1Cc1ccc(Oc2ccc(cc2F)C(N)=O)c(Cl)c1
InChI Key InChIKey=ZSXFIQRCVUEZOS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50264574
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]U69593 from recombinant human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 191nMAssay Description:Displacement of [3H]DPDPE from recombinant human delta-opioid receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu-opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting me...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at recombinant human delta-opioid receptor expressed in HEK293 cell membranes assessed as inhibition of DPDPE-induced [35S]GTPgam...More data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Antagonist activity at recombinant human mu-opioid receptor expressed in CHO cell membranes assessed as inhibition of DAMGO-induced [35S]GTPgammaS bi...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at recombinant human kappa-opioid receptor expressed in CHO cell membranes assessed as inhibition of U69593-induced [35S]GTPgamma...More data for this Ligand-Target Pair