BDBM50266041 CHEMBL4070212

SMILES C[C@@H](Oc1cc2oc(=O)n(CCC(O)=O)c2cc1Cl)c1ccccn1

InChI Key InChIKey=PVGOQRJICUIPTG-SNVBAGLBSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266041   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266041(CHEMBL4070212)
Affinity DataKi:  0.100nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Pseudomonas fluorescens)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266041(CHEMBL4070212)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of Pseudomonas fluorescens KMO expressed in Escherichia coli using kynurenine as substrate measured after 1 hr by RapidFire high-throughpu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed