BDBM50269126 CHEMBL4077551

SMILES FC(F)(F)c1cccnc1-c1cccc(c1)C(=O)Nc1cccc(c1-c1ncccc1Cl)C(F)(F)F

InChI Key InChIKey=WRIZTMCLCILPFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269126   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50269126(CHEMBL4077551)
Affinity DataIC50:  16nMAssay Description:Inhibition of slow inactivated human NaV1.7 expressed in HEK293 cells at -20 mV holding potential after 5 mins by IonWorks electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50269126(CHEMBL4077551)
Affinity DataIC50:  430nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells at -50 mV holding potential after 3 to 5 mins by PatchXpress automated electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed