BDBM50270631 3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl]-5-fluorobenzonitrile::CHEMBL487116

SMILES Fc1cc(cc(c1)-c1ccc2NC(=O)COC(c3ccco3)(c3ccco3)c2c1)C#N

InChI Key InChIKey=NDHCTRIUTPITKL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50270631   

TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50270631(3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-be...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at cloned androgen receptor-ligand binding domain expressed in african green monkey COS7 cells by two hybrid luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50270631(3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-be...)
Affinity DataIC50:  13.3nMAssay Description:Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50270631(3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-be...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at cloned mineralocorticoid receptor-ligand binding domain expressed in african green monkey COS7 cells by GAL4 luciferase report...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50270631(3-[5,5-Di(2-furyl)-2-oxo-1,2,3,5-tetrahydro-4,1-be...)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at cloned glucocorticoid receptor-ligand binding domain expressed in african green monkey COS7 cells by GAL4 luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed