BDBM50270756 CHEMBL4128807

SMILES NC(=O)C(Sc1nc(-c2cccc(c2)C(F)(F)F)c(C#N)c(=O)[nH]1)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=CNHGBJBJMTXFDT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270756   

TargetBeta-secretase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50270756(CHEMBL4128807)
Affinity DataKd:  1.03E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50270756(CHEMBL4128807)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed