BDBM50270759 CHEMBL4127412

SMILES Nc1c(Cl)cc(cc1Cl)-c1csc(NC(=O)CSc2nc(-c3cccc(c3)C(F)(F)F)c(C#N)c(=O)[nH]2)n1

InChI Key InChIKey=XYEUYJBZFFRPIN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270759   

TargetBeta-secretase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50270759(CHEMBL4127412)
Affinity DataKd:  1.33E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50270759(CHEMBL4127412)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed