BDBM50271189 9-[(2-{4-[(5,6-Dimethoxyindan-2-yl)methyl]piperidin-1-yl}ethyl)amino]-1,2,3,4-tetrahydroacridine dihydrochloride::CHEMBL486507

SMILES COc1cc2CC(CC3CCN(CCNc4c5CCCCc5nc5ccccc45)CC3)Cc2cc1OC

InChI Key InChIKey=GQLCFFCJURYPPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271189   

TargetAcetylcholinesterase(Bos taurus (bovine))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)

Curated by ChEMBL
LigandPNGBDBM50271189(9-[(2-{4-[(5,6-Dimethoxyindan-2-yl)methyl]piperidi...)
Affinity DataIC50:  2.28nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)

Curated by ChEMBL
LigandPNGBDBM50271189(9-[(2-{4-[(5,6-Dimethoxyindan-2-yl)methyl]piperidi...)
Affinity DataIC50:  8.06nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)

Curated by ChEMBL
LigandPNGBDBM50271189(9-[(2-{4-[(5,6-Dimethoxyindan-2-yl)methyl]piperidi...)
Affinity DataIC50:  5.13nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed