BDBM50271759 CHEMBL485321::N4-(3-Bromophenyl)-6-[2-(4-methoxyphenyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES COc1ccc(CCc2cc3c(Nc4cccc(Br)c4)nc(N)nc3[nH]2)cc1

InChI Key InChIKey=DDJCWGVPCKUJIU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271759   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271759(CHEMBL485321 | N4-(3-Bromophenyl)-6-[2-(4-methoxyp...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of EGFR (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271759(CHEMBL485321 | N4-(3-Bromophenyl)-6-[2-(4-methoxyp...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271759(CHEMBL485321 | N4-(3-Bromophenyl)-6-[2-(4-methoxyp...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271759(CHEMBL485321 | N4-(3-Bromophenyl)-6-[2-(4-methoxyp...)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed