BDBM50271760 CHEMBL482489::N4-(3-Bromophenyl)-6-[2-(2-chlorophenyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(CCc3ccccc3Cl)[nH]c2n1
InChI Key InChIKey=ZFOINLDOMHQFOQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50271760
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of EGFR (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 4.23E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair