BDBM50271761 CHEMBL484108::N4-(3-Bromophenyl)-6-[2-(1-naphthyl)ethyl]-7Hpyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(CCc3cccc4ccccc34)[nH]c2n1

InChI Key InChIKey=QMVUXJFOCASEQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271761   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271761(CHEMBL484108 | N4-(3-Bromophenyl)-6-[2-(1-naphthyl...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of EGFR (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271761(CHEMBL484108 | N4-(3-Bromophenyl)-6-[2-(1-naphthyl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271761(CHEMBL484108 | N4-(3-Bromophenyl)-6-[2-(1-naphthyl...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed