BDBM50271851 CHEMBL519147::N4-(4-Chlorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d ]pyrimidine-2,4-diamine

SMILES Nc1nc(Nc2ccc(Cl)cc2)c2cc(CCc3ccccc3)[nH]c2n1

InChI Key InChIKey=ATKPRIDFHGQMAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271851   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271851(CHEMBL519147 | N4-(4-Chlorophenyl)-6-(2-phenylethy...)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of EGFR (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271851(CHEMBL519147 | N4-(4-Chlorophenyl)-6-(2-phenylethy...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDGFRbeta (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271851(CHEMBL519147 | N4-(4-Chlorophenyl)-6-(2-phenylethy...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271851(CHEMBL519147 | N4-(4-Chlorophenyl)-6-(2-phenylethy...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VEGFR1 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed