BDBM50271852 CHEMBL482715::N4-(4-fluoro-3-(trifluoromethyl)phenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::N4-[4-Fluoro-3-(trifluoromethyl)phenyl]-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
SMILES Nc1nc(Nc2ccc(F)c(c2)C(F)(F)F)c2cc(CCc3ccccc3)[nH]c2n1
InChI Key InChIKey=DZLMUJLCCUJDSO-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50271852
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of EGFR (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VEGFR1 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair