BDBM50271908 CHEMBL502015::N4-(3-bromophenyl)-2-(naphthalen-2-ylmethyl)-1H-indole-4,6-diamine

SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3ccc4ccccc4c3)[nH]c2n1

InChI Key InChIKey=HLFVKVGHXYAKHL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50271908   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDGFRbeta (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50271908(CHEMBL502015 | N4-(3-bromophenyl)-2-(naphthalen-2-...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of EGFR (unknown origin) expressed in human tumor cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed