BDBM50272874 CHEMBL525530::N-(2-(1H-Indol-3-yl)ethyl)-4'-tert-butylbiphenyl-2-carboxamide

SMILES CC(C)(C)c1ccc(cc1)-c1ccccc1C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=DDZYJWMNPLPNTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50272874   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50272874(CHEMBL525530 | N-(2-(1H-Indol-3-yl)ethyl)-4'-tert-...)
Affinity DataIC50:  2.62E+5nMAssay Description:Inhibition of human CDK2/GST-cyclin A expressed in Sf9 cells assessed as histone phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50272874(CHEMBL525530 | N-(2-(1H-Indol-3-yl)ethyl)-4'-tert-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed