BDBM50273852 9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxaldehyde guanylhydrazone::CHEMBL456594

SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-[#6]-1=[#6](Cl)-c2ccccc2-[#6]-[#6]-[#6]-1

InChI Key InChIKey=GQGNCDWOCROBBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50273852   

TargetEstrogen receptor(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnvelope glycoprotein gp160(Maedi visna virus (strain 1514) (MVV) (Visna lenti...)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50:  3.60E+3nMAssay Description:Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 100 nM estradiol-induced tran...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnvelope glycoprotein gp70(Mouse mammary tumor virus (strain GR) (MMTV))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha (unknown origin) expressed in human HEC1 cells after 24 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273852(9-Chloro-6,7-dihydro-5-benzocycloheptene-8-carboxa...)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at estrogen receptor alpha (unknown origin) expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed