BDBM50274715 CHEMBL515364::N-(2-(dimethylamino)ethyl)-2-(4-(4-methylpiperazin-1-yl)phenyl)quinazolin-4-amine

SMILES CN(C)CCNc1nc(nc2ccccc12)-c1ccc(cc1)N1CCN(C)CC1

InChI Key InChIKey=QYSDZDWFJBQSFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274715   

TargetToll-like receptor 9(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274715(CHEMBL515364 | N-(2-(dimethylamino)ethyl)-2-(4-(4-...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human TLR9 expressed in HEK293 cells assessed as blockade of CpG oligonucleotide-induced immune response by NFkappaB luciferas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed