BDBM50274961 (Z)-1-((4-Methoxybenzofuran-2-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL515996

SMILES COc1cccc2oc(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)cc12

InChI Key InChIKey=ZFIPNGYGAAREFA-NVNXTCNLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274961   

TargetPerforin-1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50274961((Z)-1-((4-Methoxybenzofuran-2-yl)methylene)-6-meth...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed