BDBM50275033 CHEMBL4126434

SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1cn(CCCc2ccc(Cl)cc2)nn1

InChI Key InChIKey=RODNKCMKPZCZKG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275033   

TargetEgl nine homolog 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275033(CHEMBL4126434)
Affinity DataIC50:  62nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using FITC-HIF1-alpha (556 to 574 residues) as substrate after 60 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275033(CHEMBL4126434)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using HIF1-alpha (556 to 574 residues) as substrate in presence of 2-OG preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed