BDBM50277292 CHEMBL515295::N-(6-methoxyquinolin-8-yl)-6-(sulfamoylamino)hexanamide

SMILES COc1cc(NC(=O)CCCCCNS(N)(=O)=O)c2ncccc2c1

InChI Key InChIKey=UYOZMTOHEYUANN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277292   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50277292(CHEMBL515295 | N-(6-methoxyquinolin-8-yl)-6-(sulfa...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50277292(CHEMBL515295 | N-(6-methoxyquinolin-8-yl)-6-(sulfa...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC1 in human 293T cells after 16 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50277292(CHEMBL515295 | N-(6-methoxyquinolin-8-yl)-6-(sulfa...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed