BDBM50278337 CHEMBL470617::Naltrexone methiodide
SMILES C[N+]1(CC2CC2)CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O
InChI Key InChIKey=JVLBPIPGETUEET-GAAHOAFPSA-O
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50278337
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant delta opioid receptor assessed as reduction in SNC80 induced [3S]-GTPgammaS bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant mu opioid receptor assessed as reduction in DAMGO-induced [3S]-GTPgammaS bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by ChEMBL
Rensselaer Polytechnic Institute
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant kappa opioid receptor assessed as reduction in U50,488H-induced [3S]-GTPgammaS bindingMore data for this Ligand-Target Pair