BDBM50279026 CHEMBL505719::rac-3-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid

SMILES COc1ccc2n(Cc3ccccc3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1

InChI Key InChIKey=NBDNTRPQGNCRGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279026   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279026(CHEMBL505719 | rac-3-(1-benzyl-5-methoxy-2-methyl-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed