BDBM50280808 CHEMBL4170865

SMILES Nc1ccncc1C(=O)N[C@@H]1[C@H](Cc2ccccc12)NC(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=QERRLDXEORDJPJ-UNMCSNQZSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280808   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280808(CHEMBL4170865)
Affinity DataIC50:  50nMAssay Description:Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280808(CHEMBL4170865)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280808(CHEMBL4170865)
Affinity DataIC50:  49nMAssay Description:Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280808(CHEMBL4170865)
Affinity DataEC50:  25nMAssay Description:In vitro inhibition of dihydrofolate reductase enzymes in Neisseria gonorrhoeaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed