BDBM50281511 Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5-oxo-5H,7H-6,12-dioxa-dibenzo[a,d]cycloocten-3-yl)-3-methyl-butyl ester::CHEMBL116226

SMILES COc1c(ccc2Oc3c(O)cc(C)cc3COC(=O)c12)[C@H](CC(C)C)OC(C)=O

InChI Key InChIKey=NUYFKDBCHFKOBT-IBGZPJMESA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50281511   

TargetOxytocin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  8.40E+3nMAssay Description:Compound was tested for its ability to inhibit binding of Oxytocin to its Oxytocin receptor in rat uterine tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested for its ability to inhibit binding of arginine vasopressin to Vasopressin receptor (V1 subtype)More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Keio University

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Keio University

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  900nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Keio University

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Keio University

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed