BDBM50282514 3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one::CHEMBL18966

SMILES Cc1ccc(COc2ccc3c(C)c(C)c(=O)oc3c2)cc1

InChI Key InChIKey=GXFXMBTYRNXLMV-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50282514   

TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  560nMAssay Description:In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  3.72E+3nMAssay Description:Inhibitory activity against monoamine oxidase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  6.20nMAssay Description:Inhibitory activity against monoamine oxidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine chloride as substrate incubated for 5 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  3.72E+3nMAssay Description:Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  6.17nMAssay Description:Inhibition of rat brain MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Geneva

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  1.38nMAssay Description:Inhibition of human supersomes MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50:  6.17nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed