BDBM50287389 CHEMBL4174767

SMILES CC[C@@]1(CC(O)=O)CCc2cc(ccc2C1=O)-c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1

InChI Key InChIKey=NRRQQQHLUUOBET-MHZLTWQESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287389   

TargetDiacylglycerol O-acyltransferase 1(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287389(CHEMBL4174767)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287389(CHEMBL4174767)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287389(CHEMBL4174767)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed