BDBM50288564 (3,5-Dimethyl-phenyl)-[(2R,4S)-4-[(quinolin-4-ylmethyl)-amino]-2-(4-trifluoromethyl-benzyl)-piperidin-1-yl]-methanone::CHEMBL419352

SMILES Cc1cc(C)cc(c1)C(=O)N1CC[C@@H](C[C@H]1Cc1ccc(cc1)C(F)(F)F)NCc1ccnc2ccccc12

InChI Key InChIKey=CIXKPLGEAAADPG-WUFINQPMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288564   

TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288564((3,5-Dimethyl-phenyl)-[(2R,4S)-4-[(quinolin-4-ylme...)
Affinity DataIC50:  11nMAssay Description:Binding affinity against NK1 receptor by displacement of [3H]-SP from bovine retina membranesMore data for this Ligand-Target Pair
In DepthDetails Article