BDBM50289558 CHEMBL40071::N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2-(3-methyl-2,6-dioxo-5-phenylmethanesulfonylamino-3,6-dihydro-2H-pyrimidin-1-yl)-acetamide

SMILES Cn1cc(NS(=O)(=O)Cc2ccccc2)c(=O)n(CC(=O)N[C@H]2CCCN(C2O)C(N)=N)c1=O

InChI Key InChIKey=QTYFXTWDKLMQPO-MBIQTGHCSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50289558   

TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  396nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  141nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTissue-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289558(CHEMBL40071 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
In DepthDetails Article