BDBM50290085 (2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL74670

SMILES CNC(=O)[C@H](NC(=O)[C@H](CC(C)C)[C@@H](CN1C(=O)c2ccccc2C1=O)C(=O)NO)C(C)(C)C

InChI Key InChIKey=KYOFVPKPPTUVKK-KURKYZTESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290085   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290085((2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290085((2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  0.5nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290085((2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In DepthDetails Article