BDBM50290467 5-[3-amino(imino)methylaminopropyl]-3-[1-benzyl-2-oxo-2-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-yl-(1R)-ethyl]-(5R)-tetrahydro-1H-2,4-imidazoledione::CHEMBL70043::CHEMBL71841

SMILES NC(=N)NCCCc1[nH]c(=O)n([C@H](Cc2ccccc2)C(=O)N2CCC3(CCc4ccccc34)CC2)c1O

InChI Key InChIKey=SBJUJMWAROQRQA-XMMPIXPASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50290467   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290467(5-[3-amino(imino)methylaminopropyl]-3-[1-benzyl-2-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Antagonistic potency for NK-1 receptor was determined in a radioligand binding assay, using IM9 human lymphoblastoma cell line.More data for this Ligand-Target Pair
In DepthDetails Article
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290467(5-[3-amino(imino)methylaminopropyl]-3-[1-benzyl-2-...)
Affinity DataIC50:  800nMAssay Description:Tested for the ability to compete with [125I]-CO13 ([125I]-Y-F-K-A-Cha-G-L-dF-R) for binding to C5a anaphylatoxin chemotactic receptor from human neu...More data for this Ligand-Target Pair
In DepthDetails Article
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290467(5-[3-amino(imino)methylaminopropyl]-3-[1-benzyl-2-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Tested for its ability to compete with [125I]C5a for binding to C5a anaphylatoxin chemotactic receptor of human neutrophil membrane preparationsMore data for this Ligand-Target Pair
In DepthDetails Article