BDBM50291760 5-Ethyl-2-isopropylamino-benzo[d][1,3]oxazin-4-one::CHEMBL145550

SMILES CCc1cccc2nc(NC(C)C)oc(=O)c12

InChI Key InChIKey=GTAYSONAZGTZAS-UHFFFAOYSA-N

Data  2 KI  2 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291760   

TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291760(5-Ethyl-2-isopropylamino-benzo[d][1,3]oxazin-4-one...)
Affinity DataKi:  0.940nMAssay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291760(5-Ethyl-2-isopropylamino-benzo[d][1,3]oxazin-4-one...)
Affinity DataKi:  1nM Kon:  0.0000661M-1s-1 Koff:  7.08E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291760(5-Ethyl-2-isopropylamino-benzo[d][1,3]oxazin-4-one...)
Affinity DataKon:  0.0000660M-1s-1Assay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed