BDBM50294003 (E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(2-fluoro-5-(trifluoromethyl)phenyl)benzamide::CHEMBL551838

SMILES Cc1ccc(cc1\C=C\n1cnc2c(NC3CC3)ncnc12)C(=O)Nc1cc(ccc1F)C(F)(F)F

InChI Key InChIKey=DFUFJHCAPIDDRE-CMDGGOBGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294003   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294003((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50:  2.36E+5nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294003((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed