BDBM50294819 CHEMBL564157::N-Cyclohexyl-4-((1R,2S,6R,7S)-3,5-dioxo-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-4-yl)-benzamide

SMILES Oc1c2[C@H]3C[C@H](C=C3)c2c(O)n1-c1ccc(cc1)C(=O)NC1CCCCC1

InChI Key InChIKey=WDGUVXTVTKEOJS-GASCZTMLSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294819   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50294819(CHEMBL564157 | N-Cyclohexyl-4-((1R,2S,6R,7S)-3,5-d...)
Affinity DataEC50: >2.50E+4nMAssay Description:Activity of N-terminus hexaHis-tagged human TNSK2 expressed in Escherichia coli BL21 (DE3) cells using biotinylated NAD+ as substrate after 90 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
The University Of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50294819(CHEMBL564157 | N-Cyclohexyl-4-((1R,2S,6R,7S)-3,5-d...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed