BDBM50295538 4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclopropyl)piperidine-1-carboxamide::CHEMBL564547

SMILES Cc1noc(n1)C1CCN(CC1)C(=O)NC1CC1c1ccccc1

InChI Key InChIKey=QTDLNCWVZXZPRJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50295538   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50:  48nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpoxide hydrolase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human mEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Nav1.5 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cav 1.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IKr channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50295538(4-(3-methyl-1,2,4-oxadiazol-5-yl)-N-(2-phenylcyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed