BDBM50295957 2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-methyl)-2-(R)-pyrrolidinyl)methoxy)pyridine::CHEMBL551062

SMILES CN1CCC[C@@H]1COc1cnc(Cl)c(OCc2ccc(Cl)nc2)c1

InChI Key InChIKey=PLBWSQXHXCLSCU-CYBMUJFWSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295957   

TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295957(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295957(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295957(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295957(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295957(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295957(2-Chloro-3-(2-chloro-5-(pyridinyl)methoxy)-5-((1-m...)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed