BDBM50296188 CHEMBL558248::trans-1-{3-[4-(3-Methyl-4,4-dioxo-3,4-dihydro-2H-4lambda*6*-benzo[1,4]oxathiin-2-yl)-phenoxy]-propyl}-pyrrolidine

SMILES C[C@@H]1[C@H](Oc2ccccc2S1(=O)=O)c1ccc(OCCCN2CCCC2)cc1

InChI Key InChIKey=ITYMMRKSCDTSQX-VGSWGCGISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296188   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296188(CHEMBL558248 | trans-1-{3-[4-(3-Methyl-4,4-dioxo-3...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of [35S]MK499 binding to human ERG transfected in HEK293 cells by microscintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296188(CHEMBL558248 | trans-1-{3-[4-(3-Methyl-4,4-dioxo-3...)
Affinity DataIC50:  0.600nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylistamine-induced [35S]GTPgammaS binding by cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed