BDBM50299797 1-(2-(benzyloxy)phenyl)piperazine::CHEMBL582928

SMILES C(Oc1ccccc1N1CCNCC1)c1ccccc1

InChI Key InChIKey=PPQUPQGZDGZYJI-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50299797   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataKi:  168nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataKi: >8.72E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50:  83nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50:  2.93E+3nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50:  5.21E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50: >1.00E+4nMAssay Description:Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed