BDBM50300060 5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one::CHEMBL574898

SMILES Clc1ccc2[nH]c-3c(CC(=O)N(Cc4ccccc4)c4ccccc-34)c2c1

InChI Key InChIKey=QOTHSGGBIBMIIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300060   

TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300060(5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benz...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300060(5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300060(5-Benzyl-9-chloro-7,12-dihydroindolo[3,2-d][1]benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed