BDBM50301303 2-(4-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]azepin-3(5H)-one::CHEMBL571288

SMILES FC(F)(F)Oc1ccc(Cn2nc3CCNCCc3cc2=O)cc1

InChI Key InChIKey=XPDUNJLKDMJEEY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301303   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301303(2-(4-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301303(2-(4-(trifluoromethoxy)benzyl)-6,7,8,9-tetrahydro-...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed