BDBM50301856 7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-amine::CHEMBL577695

SMILES FC(F)(F)c1ccc(Nc2noc3c(cccc23)C(F)(F)F)cc1

InChI Key InChIKey=RPRBCFLRKRZGKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301856   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301856(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301856(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human sEH assessed as DHET production in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301856(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50:  127nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed