BDBM50302098 3-(2-(2,2-diethylhydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL577075
SMILES CCN(CC)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O
InChI Key InChIKey=OXXWFUQKMJSKBO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50302098
Affinity DataKi: 120nMAssay Description:Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.70E+3nMAssay Description:Displacement of [125I]IL-8 from human CXCR1 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+3nMAssay Description:Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at CXCR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Antagonist activity at CXCR2 expressed in CHO cells assessed as inhibition of IL-8-induced chemotaxisMore data for this Ligand-Target Pair