BDBM50302111 CHEMBL572255::N-(4-chloro-3-(1-methyl-1H-benzo[d]imidazol-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

SMILES Cc1nc(ccc1C(=O)Nc1ccc(Cl)c(c1)-c1nc2ccccc2n1C)C(F)(F)F

InChI Key InChIKey=BXBCTGXZEZPKJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302111   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50302111(CHEMBL572255 | N-(4-chloro-3-(1-methyl-1H-benzo[d]...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Genentech

Curated by ChEMBL
LigandPNGBDBM50302111(CHEMBL572255 | N-(4-chloro-3-(1-methyl-1H-benzo[d]...)
Affinity DataIC50:  9nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed