BDBM50302139 CHEMBL570273::N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

SMILES Cc1nc(ccc1C(=O)Nc1ccc(Cl)c(c1)-c1nc2ccccc2[nH]1)C(F)(F)F

InChI Key InChIKey=OMFJEUKRJLGMIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302139   

TargetSonic hedgehog protein(Mus musculus (Mouse))
Genentech

Curated by ChEMBL
LigandPNGBDBM50302139(CHEMBL570273 | N-(3-(1H-benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  12nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed