BDBM50303039 4-(4-(naphthalen-2-yl)pyrimidin-2-ylamino)benzenesulfonamide::CHEMBL569046

SMILES NS(=O)(=O)c1ccc(Nc2nccc(n2)-c2ccc3ccccc3c2)cc1

InChI Key InChIKey=SXFKMLRIZKPLQA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303039   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303039(4-(4-(naphthalen-2-yl)pyrimidin-2-ylamino)benzenes...)
Affinity DataIC50:  310nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDickkopf-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303039(4-(4-(naphthalen-2-yl)pyrimidin-2-ylamino)benzenes...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-catenin signaling in osteosasrcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed