BDBM50303226 2-chloro-N-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)phenyl)acetamide::CHEMBL565587

SMILES Cn1c2nc(Nc3ccc(NC(=O)CCl)cc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=XOVYHZSDUHWRJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303226   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50303226(2-chloro-N-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-o...)
Affinity DataIC50:  433nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50303226(2-chloro-N-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-o...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant C-KitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50303226(2-chloro-N-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-o...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human recombinant AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50303226(2-chloro-N-(4-(6-(2,6-dichlorophenyl)-8-methyl-7-o...)
Affinity DataIC50:  135nMAssay Description:Inhibition of human recombinant P38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed