BDBM50303292 1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-(4-(piperazin-1-yl)phenyl)urea::CHEMBL576506
SMILES FC(F)(F)Cn1ncc2c(nc(nc12)-c1ccc(NC(=O)Nc2ccc(cc2)N2CCNCC2)cc1)N1CC2CCC(C1)O2
InChI Key InChIKey=NKBGMLOQTKRJCU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50303292
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Binding affinity to PI3Kalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human Flag-tagged mTOR expressed in HEK293 cells after 2 hrs by DELFIAMore data for this Ligand-Target Pair