BDBM50303670 (2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidin]-7-yl]-N-[(4,5-dichlorothiophen-2-yl)sulfonyl]prop-2-enamide::3-(1-(2,4-dichlorobenzyl)-2-oxospiro[indoline-3,2'-thiazolidine]-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide::CHEMBL585507

SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21NCCS1

InChI Key InChIKey=VCDMAGVFEFXVDY-FNORWQNLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303670   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303670((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...)
Affinity DataIC50:  880nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303670((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...)
Affinity DataIC50:  880nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303670((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303670((2E)-3-[1-(2,4-dichlorobenzyl)-2-oxo-1,2-dihydrosp...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed